产品货号：
GS4400
中文名称：
重组人BMP-2
英文名称：
Recombinant Human Bone Morphogenetic Protein 2
产品规格：
2μg
发货周期：
1～3天
产品价格：
询价
分子量：Approximately 26.0kDa,a homodimeric protein consisting of two 115 amino acid non-glycosylated polypeptide chains.
储存条件：冷冻（-20℃）
概述
Bone Morphogenetic Protein 2 is one of the BMPs,some of which belong to the TGF-beta superfamily(BMP2-7).There are more than thirteen BMPs have been discovered nowadays and they are involved in inducing cartilage and bone formation.BMP-2 is expressed in a variety of tissues including lung,spleen,brain,liver,prostate ovary and small intestine.It is a potent osteoinductive cytokine and plays its role in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite.As it shown to stimulate the production of bone,the recombinant human BMP-2 is available for orthopaedic usage and dentisty.The functional form of BMP-2 is a disulflde-linked homodimer and about 26kDa The precursor of BMP-2 is 259 a.a.,containing the 23 a.a.N-terminal signal sequence which will be cleaved by a furin-type protease to form the mature peptide.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
相关搜索：重组人BMP-2，重组人骨形成蛋白2，重组人骨形态发生蛋白2，重组人BMP2，Recombinant Human Bone Morphogenetic Protein 2
储存条件：冷冻（-20℃）
概述
Bone Morphogenetic Protein 2 is one of the BMPs,some of which belong to the TGF-beta superfamily(BMP2-7).There are more than thirteen BMPs have been discovered nowadays and they are involved in inducing cartilage and bone formation.BMP-2 is expressed in a variety of tissues including lung,spleen,brain,liver,prostate ovary and small intestine.It is a potent osteoinductive cytokine and plays its role in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite.As it shown to stimulate the production of bone,the recombinant human BMP-2 is available for orthopaedic usage and dentisty.The functional form of BMP-2 is a disulflde-linked homodimer and about 26kDa The precursor of BMP-2 is 259 a.a.,containing the 23 a.a.N-terminal signal sequence which will be cleaved by a furin-type protease to form the mature peptide.
使用说明
This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.
技术规格
| 外观 | Sterile Filtered White lyophilized(freeze-dried)powder. |
| 纯度 | ＞95%by SDS-PAGE and HPLC analyses. |
| 来源 | Escherichia coli. |
| 生物活性 | Fully biologically active when compared to standard.The ED50 as determined by inducing alkaline phosphatase production of murine ATDC5 cells is less than 200ng/ml,corresponding to a specific activity of>5.0×103 IU/mg. |
| 成分 | Lyophilized from a 0.2μmfiltered concentrated solution containing 10mMsodium citrate pH3.5. |
| 内毒素 | Less than 1 EU/μg of rHuBMP-2 as determined by LAL method. |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled H2O to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20℃.Further dilutions should be made in appropriate buffered solutions.Do not reconstitute in PBS or cell culture media. |
| 氨基酸序列 | MQAKHKQRKR LKSSCKRHPL YVDFSDVGWN DWIVAPPGYH AFYCHGECPF PLADHLNSTN HAIVQTLVNS VNSKIPKACC VPTELSAISM LYLDENEKVV LKNYQDMVVE GCGCR |
相关搜索：重组人BMP-2，重组人骨形成蛋白2，重组人骨形态发生蛋白2，重组人BMP2，Recombinant Human Bone Morphogenetic Protein 2